Unraveling the Molecular Mechanisms Underlying Complement Dysregulation by Nephritic Factors in C3G and IC-MPGN

Membranoproliferative glomerulonephritis (MPGN) was recently classified as C3 glomerulopathies (C3G), and immune-complex (IC) mediated MPGN. Dysregulation of the complement alternative pathway, driven by acquired and/or genetic defects, plays a pathogenetic role in C3G. However, alternative pathway...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Donadelli, Roberta, Pulieri, Patrizia, Piras, Rossella, Iatropoulos, Paraskevas, Valoti, Elisabetta, Benigni, Ariela, Remuzzi, Giuseppe, Noris, Marina
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248175/
https://ncbi.nlm.nih.gov/pubmed/30487789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02329
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