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Characterization of substantia nigra neurogenesis in homeostasis and dopaminergic degeneration: beneficial effects of the microneurotrophin BNN-20

BACKGROUND: Loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) underlines much of the pathology of Parkinson’s disease (PD), but the existence of an endogenous neurogenic system that could be targeted as a therapeutic strategy has been controversial. BNN-20 is a synthetic, BDN...

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Bibliografiska uppgifter
I publikationen:Stem Cell Res Ther
Huvudupphovsmän: Mourtzi, Theodora, Dimitrakopoulos, Dimitrios, Kakogiannis, Dimitrios, Salodimitris, Charalampos, Botsakis, Konstantinos, Meri, Danai Kassandra, Anesti, Maria, Dimopoulou, Aggeliki, Charalampopoulos, Ioannis, Gravanis, Achilleas, Matsokis, Nikolaos, Angelatou, Fevronia, Kazanis, Ilias
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2021
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193896/
https://ncbi.nlm.nih.gov/pubmed/34112234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02398-3
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