Characterization of substantia nigra neurogenesis in homeostasis and dopaminergic degeneration: beneficial effects of the microneurotrophin BNN-20

BACKGROUND: Loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) underlines much of the pathology of Parkinson’s disease (PD), but the existence of an endogenous neurogenic system that could be targeted as a therapeutic strategy has been controversial. BNN-20 is a synthetic, BDN...

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Publicado en:Stem Cell Res Ther
Main Authors: Mourtzi, Theodora, Dimitrakopoulos, Dimitrios, Kakogiannis, Dimitrios, Salodimitris, Charalampos, Botsakis, Konstantinos, Meri, Danai Kassandra, Anesti, Maria, Dimopoulou, Aggeliki, Charalampopoulos, Ioannis, Gravanis, Achilleas, Matsokis, Nikolaos, Angelatou, Fevronia, Kazanis, Ilias
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193896/
https://ncbi.nlm.nih.gov/pubmed/34112234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02398-3
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