Immunization with a heat-killed bacterium, Mycobacterium vaccae NCTC 11659, prevents the development of cortical hyperarousal and a PTSD-like sleep phenotype after sleep disruption and acute stress in mice

STUDY OBJECTIVES: Sleep deprivation induces systemic inflammation that may contribute to stress vulnerability and other pathologies. We tested the hypothesis that immunization with heat-killed Mycobacterium vaccae NCTC 11659 (MV), an environmental bacterium with immunoregulatory and anti-inflammator...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sleep
Main Authors: Bowers, Samuel J, Lambert, Sophie, He, Shannon, Lowry, Christopher A, Fleshner, Monika, Wright, Kenneth P, Turek, Fred W, Vitaterna, Martha H
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Basic Science of Sleep and Circadian Rhythms
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193553/
https://ncbi.nlm.nih.gov/pubmed/33283862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sleep/zsaa271
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki