Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice

The prevalence of inflammatory diseases is increasing in modern urban societies. Inflammation increases risk of stress-related pathology; consequently, immunoregulatory or antiinflammatory approaches may protect against negative stress-related outcomes. We show that stress disrupts the homeostatic r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Reber, Stefan O., Siebler, Philip H., Donner, Nina C., Morton, James T., Smith, David G., Kopelman, Jared M., Lowe, Kenneth R., Wheeler, Kristen J., Fox, James H., Hassell, James E., Greenwood, Benjamin N., Jansch, Charline, Lechner, Anja, Schmidt, Dominic, Uschold-Schmidt, Nicole, Füchsl, Andrea M., Langgartner, Dominik, Walker, Frederick R., Hale, Matthew W., Lopez Perez, Gerardo, Van Treuren, Will, González, Antonio, Halweg-Edwards, Andrea L., Fleshner, Monika, Raison, Charles L., Rook, Graham A., Peddada, Shyamal D., Knight, Rob, Lowry, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896712/
https://ncbi.nlm.nih.gov/pubmed/27185913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600324113
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