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Logical modelling of in vitro differentiation of human monocytes into dendritic cells unravels novel transcriptional regulatory interactions

Dendritic cells (DCs) are the major specialized antigen-presenting cells, thereby connecting innate and adaptive immunity. Because of their role in establishing adaptive immunity, they constitute promising targets for immunotherapy. Monocytes can differentiate into DCs in vitro in the presence of co...

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Detalhes bibliográficos
Publicado no:Interface Focus
Main Authors: Nuñez-Reza, Karen J., Naldi, Aurélien, Sánchez-Jiménez, Arantza, Leon-Apodaca, Ana V., Santana, M. Angélica, Thomas-Chollier, Morgane, Thieffry, Denis, Medina-Rivera, Alejandra
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193469/
https://ncbi.nlm.nih.gov/pubmed/34123352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2020.0061
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