RSAT variation-tools: An accessible and flexible framework to predict the impact of regulatory variants on transcription factor binding

Gene regulatory regions contain short and degenerated DNA binding sites recognized by transcription factors (TFBS). When TFBS harbor SNPs, the DNA binding site may be affected, thereby altering the transcriptional regulation of the target genes. Such regulatory SNPs have been implicated as causal va...

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Dades bibliogràfiques
Publicat a:Comput Struct Biotechnol J
Autors principals: Santana-Garcia, Walter, Rocha-Acevedo, Maria, Ramirez-Navarro, Lucia, Mbouamboua, Yvon, Thieffry, Denis, Thomas-Chollier, Morgane, Contreras-Moreira, Bruno, van Helden, Jacques, Medina-Rivera, Alejandra
Format: Artigo
Idioma:Inglês
Publicat: Research Network of Computational and Structural Biotechnology 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906655/
https://ncbi.nlm.nih.gov/pubmed/31871587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.09.009
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