Structure-based redesigning of pentoxifylline analogs against selective phosphodiesterases to modulate sperm functional competence for assisted reproductive technologies

Phosphodiesterase (PDE) inhibitors, such as pentoxifylline (PTX), are used as pharmacological agents to enhance sperm motility in assisted reproductive technology (ART), mainly to aid the selection of viable sperm in asthenozoospermic ejaculates and testicular spermatozoa, prior to intracytoplasmic...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Satish, Mutyala, Kumari, Sandhya, Deeksha, Waghela, Abhishek, Suman, Nitin, Kulhar, Adiga, Satish Kumar, Hegde, Padmaraj, Dasappa, Jagadeesh Prasad, Kalthur, Guruprasad, Rajakumara, Eerappa
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192908/
https://ncbi.nlm.nih.gov/pubmed/34112881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91636-y
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires