Design and Microwave Assisted Synthesis of Coumarin Derivatives as PDE Inhibitors

Coumarins appended to benzimidazole through pyrazole are designed and synthesized using microwave irradiation. These compounds were analyzed for phosphodiesterase (PDE) inhibition indirectly by motility pattern in human spermatozoa. Some of the synthesized compounds, namely, 5d, 5e, 5f, 5g, 5h, and...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Med Chem
Main Authors: Kumbar, Mahadev N., Kamble, Ravindra R., Kamble, Atulkumar A., Salian, Sujith Raj, Kumari, Sandhya, Nair, Ramya, Kalthur, Guruprasad, Adiga, Satish Kumar, Prasad, D. Jagadeesh
פורמט: Artigo
שפה:Inglês
יצא לאור: Hindawi Publishing Corporation 2016
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779523/
https://ncbi.nlm.nih.gov/pubmed/26998358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9890630
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