Peroxidasin promotes diabetic vascular endothelial dysfunction induced by advanced glycation end products via NOX2/HOCl/Akt/eNOS pathway

Reactive oxygen species (ROS) derived from NADPH oxidases (NOX) plays an essential role in advanced glycation end products (AGEs)-induced diabetic vascular endothelial dysfunction. Peroxidasin (PXDN, VPO1) is one member of peroxidases family that catalyzes hydrogen peroxide (H(2)O(2)) to hypochlorou...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Jing Cao, Zhang, Guogang, Liu, Zhaoya, Xu, Qian, Li, Chan, Cheng, Guangjie, Shi, Ruizheng
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192873/
https://ncbi.nlm.nih.gov/pubmed/34116361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.102031
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