Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells

The pancreas is comprised of exocrine and endocrine compartments releasing digestive enzymes into the duodenum and regulating blood glucose levels by insulin and glucagon release. Tissue homeostasis is depending on transcription factor networks, involving Ptf1α, Ngn3, Nkx6.1, and Sox9, which are alr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Discov
Prif Awduron: Lasierra Losada, María, Pauler, Melissa, Vandamme, Niels, Goossens, Steven, Berx, Geert, Leppkes, Moritz, Schuhwerk, Harald, Brabletz, Simone, Brabletz, Thomas, Stemmler, Marc P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192546/
https://ncbi.nlm.nih.gov/pubmed/34112759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00522-z
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