Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells

The pancreas is comprised of exocrine and endocrine compartments releasing digestive enzymes into the duodenum and regulating blood glucose levels by insulin and glucagon release. Tissue homeostasis is depending on transcription factor networks, involving Ptf1α, Ngn3, Nkx6.1, and Sox9, which are alr...

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Bibliographic Details
Published in:Cell Death Discov
Main Authors: Lasierra Losada, María, Pauler, Melissa, Vandamme, Niels, Goossens, Steven, Berx, Geert, Leppkes, Moritz, Schuhwerk, Harald, Brabletz, Simone, Brabletz, Thomas, Stemmler, Marc P.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192546/
https://ncbi.nlm.nih.gov/pubmed/34112759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00522-z
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