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Repeat RNA expansion disorders of the nervous system: post-transcriptional mechanisms and therapeutic strategies
Dozens of incurable neurological disorders result from expansion of short repeat sequences in both coding and non-coding regions of the transcriptome. Short repeat expansions underlie microsatellite repeat expansion (MRE) disorders including myotonic dystrophy (DM1, CUG(50–3,500) in DMPK; DM2, CCTG(...
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| Publicado no: | Crit Rev Biochem Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8192115/ https://ncbi.nlm.nih.gov/pubmed/33172304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2020.1841726 |
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