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Repeat RNA expansion disorders of the nervous system: post-transcriptional mechanisms and therapeutic strategies
Dozens of incurable neurological disorders result from expansion of short repeat sequences in both coding and non-coding regions of the transcriptome. Short repeat expansions underlie microsatellite repeat expansion (MRE) disorders including myotonic dystrophy (DM1, CUG(50–3,500) in DMPK; DM2, CCTG(...
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| 出版年: | Crit Rev Biochem Mol Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8192115/ https://ncbi.nlm.nih.gov/pubmed/33172304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2020.1841726 |
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