A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies

Polycomb group (PcG) proteins are widely utilized for transcriptional repression in eukaryotes. Here, we characterize, in the protist Tetrahymena thermophila, the EZL1 (E(z)-like 1) complex, with components conserved in metazoan Polycomb Repressive Complexes 1 and 2 (PRC1 and PRC2). The EZL1 complex...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Xu, Jing, Zhao, Xiaolu, Mao, Fengbiao, Basrur, Venkatesha, Ueberheide, Beatrix, Chait, Brian T, Allis, C David, Taverna, Sean D, Gao, Shan, Wang, Wei, Liu, Yifan
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2021
Предметы:
NAR Breakthrough Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191774/
https://ncbi.nlm.nih.gov/pubmed/33412588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1262
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