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RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena
Methylated H3K27 is an important mark for Polycomb group (PcG) protein-mediated transcriptional gene silencing (TGS) in multicellular eukaryotes. Here a Drosophila E(z) homolog, EZL1, is characterized in the ciliated protozoan Tetrahymena thermophila and is shown to be responsible for H3K27 methylat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1891430/ https://ncbi.nlm.nih.gov/pubmed/17575054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1544207 |
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