RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena

Methylated H3K27 is an important mark for Polycomb group (PcG) protein-mediated transcriptional gene silencing (TGS) in multicellular eukaryotes. Here a Drosophila E(z) homolog, EZL1, is characterized in the ciliated protozoan Tetrahymena thermophila and is shown to be responsible for H3K27 methylat...

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Bibliographic Details
Main Authors: Liu, Yifan, Taverna, Sean D., Muratore, Tara L., Shabanowitz, Jeffrey, Hunt, Donald F., Allis, C. David
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891430/
https://ncbi.nlm.nih.gov/pubmed/17575054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1544207
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