Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis

Despite the well-established role of heterochromatin in protecting chromosomal integrity during meiosis and mitosis, the contribution and extent of heterochromatic histone posttranslational modifications (PTMs) remain poorly defined. Here, we gained novel functional insight about heterochromatic PTM...

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Autors principals: Papazyan, Romeo, Voronina, Ekaterina, Chapman, Jessica R, Luperchio, Teresa R, Gilbert, Tonya M, Meier, Elizabeth, Mackintosh, Samuel G, Shabanowitz, Jeffrey, Tackett, Alan J, Reddy, Karen L, Coyne, Robert S, Hunt, Donald F, Liu, Yifan, Taverna, Sean D
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2014
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141274/
https://ncbi.nlm.nih.gov/pubmed/25161194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02996
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