A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies

Polycomb group (PcG) proteins are widely utilized for transcriptional repression in eukaryotes. Here, we characterize, in the protist Tetrahymena thermophila, the EZL1 (E(z)-like 1) complex, with components conserved in metazoan Polycomb Repressive Complexes 1 and 2 (PRC1 and PRC2). The EZL1 complex...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Xu, Jing, Zhao, Xiaolu, Mao, Fengbiao, Basrur, Venkatesha, Ueberheide, Beatrix, Chait, Brian T, Allis, C David, Taverna, Sean D, Gao, Shan, Wang, Wei, Liu, Yifan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
NAR Breakthrough Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191774/
https://ncbi.nlm.nih.gov/pubmed/33412588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1262
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