A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies

Polycomb group (PcG) proteins are widely utilized for transcriptional repression in eukaryotes. Here, we characterize, in the protist Tetrahymena thermophila, the EZL1 (E(z)-like 1) complex, with components conserved in metazoan Polycomb Repressive Complexes 1 and 2 (PRC1 and PRC2). The EZL1 complex...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Xu, Jing, Zhao, Xiaolu, Mao, Fengbiao, Basrur, Venkatesha, Ueberheide, Beatrix, Chait, Brian T, Allis, C David, Taverna, Sean D, Gao, Shan, Wang, Wei, Liu, Yifan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
NAR Breakthrough Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191774/
https://ncbi.nlm.nih.gov/pubmed/33412588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1262
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