A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies

Polycomb group (PcG) proteins are widely utilized for transcriptional repression in eukaryotes. Here, we characterize, in the protist Tetrahymena thermophila, the EZL1 (E(z)-like 1) complex, with components conserved in metazoan Polycomb Repressive Complexes 1 and 2 (PRC1 and PRC2). The EZL1 complex...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Xu, Jing, Zhao, Xiaolu, Mao, Fengbiao, Basrur, Venkatesha, Ueberheide, Beatrix, Chait, Brian T, Allis, C David, Taverna, Sean D, Gao, Shan, Wang, Wei, Liu, Yifan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
NAR Breakthrough Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191774/
https://ncbi.nlm.nih.gov/pubmed/33412588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1262
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