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The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II

The Cdk8 kinase module (CKM) is a dissociable part of the coactivator complex mediator, which regulates gene transcription by RNA polymerase II. The CKM has both negative and positive functions in gene transcription that remain poorly understood at the mechanistic level. In order to reconstitute the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Osman, Sara, Mohammad, Eusra, Lidschreiber, Michael, Stuetzer, Alexandra, Bazsó, Fanni Laura, Maier, Kerstin C., Urlaub, Henning, Cramer, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191332/
https://ncbi.nlm.nih.gov/pubmed/33933450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100734
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