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Molecular and in vivo Functions of the CDK8 and CDK19 Kinase Modules

CDK8 and its paralog, CDK19, collectively termed ‘Mediator Kinase,’ are cyclin-dependent kinases that have been implicated as key rheostats in cellular homeostasis and developmental programming. CDK8 and CDK19 are incorporated, in a mutually exclusive manner, as part of a 4-protein complex called th...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Dannappel, Marius Volker, Sooraj, Dhanya, Loh, Jia Jian, Firestein, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340071/
https://ncbi.nlm.nih.gov/pubmed/30693281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00171
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