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Total in vitro biosynthesis of the nonribosomal macrolactone peptide valinomycin

Natural products are important because of their significant pharmaceutical properties such as antiviral, antimicrobial, and anticancer activity. Recent breakthroughs in DNA sequencing reveal that a great number of cryptic natural product biosynthetic gene clusters are encoded in microbial genomes, f...

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Bibliographic Details
Published in:Metab Eng
Main Authors: Zhuang, Lei, Huang, Shuhui, Liu, Wan-Qiu, Karim, Ashty S., Jewett, Michael C., Li, Jian
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190601/
https://ncbi.nlm.nih.gov/pubmed/32224263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2020.03.009
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