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Total Biosynthesis and Diverse Applications of the Nonribosomal Peptide-Polyketide Siderophore Yersiniabactin

Yersiniabactin (Ybt) is a mixed nonribosomal peptide-polyketide natural product natively produced by the pathogen Yersinia pestis. The compound enables iron scavenging capabilities upon host infection and is biosynthesized by a nonribosomal peptide synthetase featuring a polyketide synthase module....

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Ahmadi, Mahmoud Kamal, Fawaz, Samar, Jones, Charles H., Zhang, Guojian, Pfeifer, Blaine A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510178/
https://ncbi.nlm.nih.gov/pubmed/26025901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01373-15
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