Plasma Adenosine Deaminase (ADA)-1 and -2 Demonstrate Robust Ontogeny Across the First Four Months of Human Life

BACKGROUND: Human adenosine deaminases (ADAs) modulate the immune response: ADA1 via metabolizing adenosine, a purine metabolite that inhibits pro-inflammatory and Th1 cytokine production, and the multi-functional ADA2, by enhancing T-cell proliferation and monocyte differentiation. Newborns are rel...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Odumade, Oludare A., Plotkin, Alec L., Pak, Jensen, Idoko, Olubukola T., Pettengill, Matthew A., Kollmann, Tobias R., Ozonoff, Al, Kampmann, Beate, Levy, Ofer, Smolen, Kinga K.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190399/
https://ncbi.nlm.nih.gov/pubmed/34122398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.578700
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