Soluble Ecto-5′-nucleotidase (5′-NT), Alkaline Phosphatase, and Adenosine Deaminase (ADA1) Activities in Neonatal Blood Favor Elevated Extracellular Adenosine

Extracellular adenosine, a key regulator of physiology and immune cell function that is found at elevated levels in neonatal blood, is generated by phosphohydrolysis of adenine nucleotides released from cells and catabolized by deamination to inosine. Generation of adenosine monophosphate (AMP) in b...

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Detalhes bibliográficos
Main Authors: Pettengill, Matthew, Robson, Simon, Tresenriter, Megan, Millán, José Luis, Usheva, Anny, Bingham, Taiese, Belderbos, Mirjam, Bergelson, Ilana, Burl, Sarah, Kampmann, Beate, Gelinas, Laura, Kollmann, Tobias, Bont, Louis, Levy, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779727/
https://ncbi.nlm.nih.gov/pubmed/23897810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.484212
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