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Cystine–glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice

xCT is the specific subunit of System xc-, an antiporter importing cystine while releasing glutamate. Although xCT expression has been found in the spinal cord, its expression and role after spinal cord injury (SCI) remain unknown. The aim of this study was to characterize the role of xCT on functio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sprimont, Lindsay, Janssen, Pauline, De Swert, Kathleen, Van Bulck, Mathias, Rooman, Ilse, Gilloteaux, Jacques, Massie, Ann, Nicaise, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190126/
https://ncbi.nlm.nih.gov/pubmed/34108554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91698-y
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