NO(•)/RUNX3/kynurenine metabolic signaling enhances disease aggressiveness in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy and is refractory to available treatments. Delineating the regulatory mechanisms of metabolic reprogramming, a key event in pancreatic cancer progression, may identify candidate targets with potential therapeutic significance. We hypothe...

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Pubblicato in:Int J Cancer
Autori principali: Wang, Limin, Tang, Wei, Yang, Shouhui, He, Peijun, Wang, Jian, Gaedcke, Jochen, Ströbel, Philipp, Azizian, Azadeh, Ried, Thomas, Gaida, Matthias M., Yfantis, Harris G., Lee, Dong H., Lal, Ashish, Van den Eynde, Benoit J., Alexander, H. Richard, Ghadimi, B. Michael, Hanna, Nader, Hussain, S. Perwez
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189162/
https://ncbi.nlm.nih.gov/pubmed/31609478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32733
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