Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer

PURPOSE: To identify metabolic pathways that are perturbed in pancreatic ductal adenocarcinoma (PDAC), we investigated gene-metabolite networks with integration of metabolomics and transcriptomics. EXPERIMENTAL DESIGN: We have performed global metabolite profiling analysis on two independent cohorts...

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Détails bibliographiques
Auteurs principaux: Zhang, Geng, He, Peijun, Tan, Hanson, Budhu, Anuradha, Gaedcke, Jochen, Ghadimi, B. Michael, Ried, Thomas, Yfantis, Harris G., Lee, Dong H., Maitra, Anirban, Hanna, Nader, Alexander, H. Richard, Hussain, S. Perwez
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778077/
https://ncbi.nlm.nih.gov/pubmed/23918603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0209
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