Macrophage Migration Inhibitory Factor (MIF) Induces Epithelial to Mesenchymal Transition, Enhances Tumor Aggressiveness and Predicts Clinical Outcome in Resected Pancreatic Ductal Adenocarcinoma

MIF is a pro-inflammatory cytokine and is implicated in cancer. A higher MIF level is found in many human cancer and cancer-prone inflammatory diseases, including chronic pancreatitis and pancreatic cancer. We tested the hypothesis that MIF contributes to pancreatic cancer aggressiveness and predict...

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Autori principali: Funamizu, Naotake, Hu, Chaoxin, Lacy, Curtis, Schetter, Aaron, Zhang, Geng, He, Peijun, Gaedcke, Jochen, Ghadimi, B. Michael, Ried, Thomas, Yfantis, Harris G., Lee, Dong H., Subleski, Jeffrey, Chan, Tim, Weiss, Jonathan M., Back, Timothy C., Yanaga, Katsuhiko, Hanna, Nader, Alexander, H. Richard, Maitra, Anirban, Hussain, S. Perwez
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488363/
https://ncbi.nlm.nih.gov/pubmed/22821831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27736
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