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Nanoparticles Engineered as Artificial Antigen-Presenting Cells Induce Human CD4(+) and CD8(+) Tregs That Are Functional in Humanized Mice

Artificial antigen-presenting cells (aAPCs) are synthetic versions of naturally occurring antigen-presenting cells (APCs) that, similar to natural APCs, promote efficient T effector cell responses in vitro. This report describes a method to produce acellular tolerogenic aAPCs made of biodegradable p...

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Библиографические подробности
Опубликовано в: :Front Immunol
Главные авторы: Giang, Sophia, Horwitz, David A., Bickerton, Sean, La Cava, Antonio
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189151/
https://ncbi.nlm.nih.gov/pubmed/34122401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.628059
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