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The mRNA-Binding Protein HuR Is a Kinetically-Privileged Electrophile Sensor

The key mRNA-binding proteins HuR and AUF1 are reported stress sensors in mammals. Intrigued by recent reports of sensitivity of these proteins to the electrophilic lipid prostaglandin A2 and other redox signals, we here examined their sensing abilities to a prototypical redox-linked lipid-derived e...

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Bibliografiske detaljer
Udgivet i:Helv Chim Acta
Main Authors: Poganik, Jesse R., Van Hall-Beauvais, Alexandra K., Long, Marcus J. C., Disare, Michael T., Zhao, Yi, Aye, Yimon
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188987/
https://ncbi.nlm.nih.gov/pubmed/34113045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hlca.202000041
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