Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1

The nuclear factor erythroid 2–related factor 2 (Nrf2) signaling axis is a target of covalent drugs and bioactive native electrophiles. However, much of our understanding of Nrf2 regulation has been focused at the protein level. Here we report a post-transcriptional modality to directly regulate Nrf...

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Vydáno v:FASEB J
Hlavní autoři: Poganik, Jesse R., Long, Marcus J. C., Disare, Michael T., Liu, Xuyu, Chang, Sung-Hee, Hla, Timothy, Aye, Yimon
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993928/
https://ncbi.nlm.nih.gov/pubmed/31665914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901930R
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