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MicroRNA-92b augments sorafenib resistance in hepatocellular carcinoma via targeting PTEN to activate PI3K/AKT/mTOR signaling

Sorafenib (SOR) resistance is still a significant challenge for the effective treatment of hepatocellular carcinoma (HCC). The mechanism of sorafenib resistance remains unclear. Several microRNAs (miRNAs) have been identified as playing a role in impairing the sensitivity of tumor cells to treatment...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Braz J Med Biol Res
Hauptverfasser: Cheng, Zhouyang, Ni, Qingfeng, Qin, Lei, Shi, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Associação Brasileira de Divulgação Científica 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186377/
https://ncbi.nlm.nih.gov/pubmed/34076140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X2020e10390
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