Generating CAR T cells from tumor-infiltrating lymphocytes

Background: Tumor-infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T-cell therapies have demonstrated promising, though limited, efficacy against melanoma. Methods: We designed a model system to explore the efficacy of dual specific T cells derived from melanoma patient TILs by tr...

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Detalles Bibliográficos
Publicado en:Ther Adv Vaccines Immunother
Autores principales: Mills, Jane K., Henderson, Melissa A., Giuffrida, Lauren, Petrone, Pasquale, Westwood, Jennifer A., Darcy, Phillip K., Neeson, Paul J., Kershaw, Michael H., Gyorki, David E.
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2021
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186112/
https://ncbi.nlm.nih.gov/pubmed/34159293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/25151355211017119
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