A HIF1α-GPD1 feedforward loop inhibits the progression of renal clear cell carcinoma via mitochondrial function and lipid metabolism

BACKGROUND: Hypoxia signaling, especially the hypoxia inducible factor (HIF) pathway, is a major player in clear cell renal cell carcinoma (ccRCC), which is characterized by disorders in lipid and glycogen metabolism. However, the interaction between hypoxia and lipid metabolism in ccRCC progression...

詳細記述

保存先:
書誌詳細
出版年:J Exp Clin Cancer Res
主要な著者: Liu, Ren, Feng, Yuanfa, Deng, Yulin, Zou, Zhihao, Ye, Jianheng, Cai, Zhiduan, Zhu, Xuejin, Liang, Yingke, Lu, Jianming, Zhang, Hui, Luo, Yong, Han, Zhaodong, Zhuo, Yangjia, Xie, Qingling, Hon, Chi Tin, Liang, Yuxiang, Wu, Chin-Lee, Zhong, Weide
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185942/
https://ncbi.nlm.nih.gov/pubmed/34098990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01996-6
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