TFEB Promotes Prostate Cancer Progression via Regulating ABCA2-Dependent Lysosomal Biogenesis

Transcription factor EB (TFEB), a member of the MiT family, is dysregulated in different cancers and exerts specific biological functions within the tumor microenvironment. Downregulation of TFEB induces macrophage polarization in the TME and promotes tumor progression. However, the biological role...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Zhu, Xuejin, Zhuo, Yangjia, Wu, Shulin, Chen, Yanfei, Ye, Jianheng, Deng, Yulin, Feng, Yuanfa, Liu, Ren, Cai, Shanghua, Zou, Zhihao, Wang, Bin, Wu, Chin-Lee, Zeng, Guohua, Zhong, Weide
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959325/
https://ncbi.nlm.nih.gov/pubmed/33732651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.632524
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