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Redox modifications of cysteine residues regulate the cytokine activity of HMGB1
BACKGROUND: High mobility group box 1 (HMGB1) is a nuclear protein with extracellular inflammatory cytokine activity. It is passively released during cell death and secreted by activated cells of many lineages. HMGB1 contains three conserved redox-sensitive cysteine residues: cysteines in position 2...
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| Publicado no: | Mol Med |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8185929/ https://ncbi.nlm.nih.gov/pubmed/34098868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-021-00307-1 |
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