SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2

In this study we profiled vaccine-induced polyclonal antibodies as well as plasmablast-derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal antibody responses in vaccinees were robust and comparable to or exceeded those seen after natural infection. However, the ratio...

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Udgivet i:Cell
Main Authors: Amanat, Fatima, Thapa, Mahima, Lei, Tinting, Ahmed, Shaza M. Sayed, Adelsberg, Daniel C., Carreño, Juan Manuel, Strohmeier, Shirin, Schmitz, Aaron J., Zafar, Sarah, Zhou, Julian Q., Rijnink, Willemijn, Alshammary, Hala, Borcherding, Nicholas, Reiche, Ana Gonzalez, Srivastava, Komal, Sordillo, Emilia Mia, van Bakel, Harm, Turner, Jackson S., Bajic, Goran, Simon, Viviana, Ellebedy, Ali H., Krammer, Florian
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Inc. 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185186/
https://ncbi.nlm.nih.gov/pubmed/34192529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.06.005
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