Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses

Macrophages initiate inflammatory responses via the transcription factor NFκB. The temporal pattern of NFκB activity determines which genes are expressed and thus, the type of response that ensues. Here, we examined how information about the stimulus is encoded in the dynamics of NFκB activity. We g...

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Vydáno v:Immunity
Hlavní autoři: Adelaja, Adewunmi, Taylor, Brooks, Sheu, Katherine M., Liu, Yi, Luecke, Stefanie, Hoffmann, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184127/
https://ncbi.nlm.nih.gov/pubmed/33979588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.04.011
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