An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms

Nuclear factor kappa B (NFκB) is a transcription factor that controls inflammation and cell survival. In clinical histology, elevated NFκB activity is a hallmark of poor prognosis in inflammatory disease and cancer, and may be the result of a combination of diverse micro-environmental constituents....

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mitchell, Simon, Mercado, Ellen L., Adelaja, Adewunmi, Ho, Jessica Q., Cheng, Quen J., Ghosh, Gourisankar, Hoffmann, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604663/
https://ncbi.nlm.nih.gov/pubmed/31293585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01425
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