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CryoDRGN: Reconstruction of heterogeneous cryo-EM structures using neural networks
Cryo-EM single-particle analysis has proven powerful in determining the structures of rigid macromolecules. However, many imaged protein complexes exhibit complex conformational and compositional heterogeneity that pose a major challenge to existing 3D reconstruction methods. Here, we present cryoDR...
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| Publicado no: | Nat Methods |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8183613/ https://ncbi.nlm.nih.gov/pubmed/33542510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-01049-4 |
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