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Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs

Cryo-electron microscopy is a popular method for protein structure determination. Identifying a sufficient number of particles for analysis can take months of manual effort. Current computational approaches find many false positives and require significant ad hoc post-processing, especially for unus...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Bepler, Tristan, Morin, Andrew, Rapp, Micah, Brasch, Julia, Shapiro, Lawrence, Noble, Alex J., Berger, Bonnie
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858545/
https://ncbi.nlm.nih.gov/pubmed/31591578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0575-8
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