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Cryo-EM reconstruction of continuous heterogeneity by Laplacian spectral volumes

Single-particle electron cryomicroscopy is an essential tool for high-resolution 3D reconstruction of proteins and other biological macromolecules. An important challenge in cryo-EM is the reconstruction of non-rigid molecules with parts that move and deform. Traditional reconstruction methods fail...

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Detalhes bibliográficos
Publicado no:Inverse Probl
Main Authors: Moscovich, Amit, Halevi, Amit, Andén, Joakim, Singer, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213598/
https://ncbi.nlm.nih.gov/pubmed/32394996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1361-6420/ab4f55
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