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Mitochondrial metabolism promotes adaptation to proteotoxic stress
The mechanisms by which cells adapt to proteotoxic stress are largely unknown, but key to understanding how tumor cells, particularly in vivo, are largely resistant to proteasome inhibitors. Analysis of cancer cell lines, mouse xenografts and patient-derived tumor samples all showed an association b...
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| הוצא לאור ב: | Nat Chem Biol |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8183600/ https://ncbi.nlm.nih.gov/pubmed/31133756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0291-9 |
| תגים: |
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