A Ca(2+)-Dependent Switch Activates Axonal Casein Kinase 2α Translation and Drives G3BP1 Granule Disassembly for Axon Regeneration

The main limitation on axon regeneration in the peripheral nervous system (PNS) is the slow rate of regrowth. We recently reported that nerve regeneration can be accelerated by axonal G3BP1 granule disassembly, releasing axonal mRNAs for local translation to support axon growth. Here, we show that G...

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Vydáno v:Curr Biol
Hlavní autoři: Sahoo, Pabitra K., Kar, Amar N., Samra, Nitzan, Terenzio, Marco, Patel, Priyanka, Lee, Seung Joon, Miller, Sharmina, Thames, Elizabeth, Jones, Blake, Kawaguchi, Riki, Coppola, Giovanni, Fainzilber, Mike, Twiss, Jeffery L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8182743/
https://ncbi.nlm.nih.gov/pubmed/33065005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.09.043
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