A Ca(2+)-Dependent Switch Activates Axonal Casein Kinase 2α Translation and Drives G3BP1 Granule Disassembly for Axon Regeneration

The main limitation on axon regeneration in the peripheral nervous system (PNS) is the slow rate of regrowth. We recently reported that nerve regeneration can be accelerated by axonal G3BP1 granule disassembly, releasing axonal mRNAs for local translation to support axon growth. Here, we show that G...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Sahoo, Pabitra K., Kar, Amar N., Samra, Nitzan, Terenzio, Marco, Patel, Priyanka, Lee, Seung Joon, Miller, Sharmina, Thames, Elizabeth, Jones, Blake, Kawaguchi, Riki, Coppola, Giovanni, Fainzilber, Mike, Twiss, Jeffery L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8182743/
https://ncbi.nlm.nih.gov/pubmed/33065005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.09.043
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