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Selective axonal translation of the mRNA isoform encoding prenylated Cdc42 supports axon growth
The small Rho-family GTPase Cdc42 has long been known to have a role in cell motility and axon growth. The eukaryotic Ccd42 gene is alternatively spliced to generate mRNAs with two different 3′ untranslated regions (UTRs) that encode proteins with distinct C-termini. The C-termini of these Cdc42 pro...
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| Publicat a: | J Cell Sci |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Company of Biologists Ltd
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8077440/ https://ncbi.nlm.nih.gov/pubmed/33674450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.251967 |
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