The CNS-Penetrant Soluble Guanylate Cyclase Stimulator CY6463 Reveals its Therapeutic Potential in Neurodegenerative Diseases

Effective treatments for neurodegenerative diseases remain elusive and are critically needed since the burden of these diseases increases across an aging global population. Nitric oxide (NO) is a gasotransmitter that binds to soluble guanylate cyclase (sGC) to produce cyclic guanosine monophosphate...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Correia, Susana S., Iyengar, Rajesh R., Germano, Peter, Tang, Kim, Bernier, Sylvie G., Schwartzkopf, Chad D., Tobin, Jenny, Lee, Thomas W.-H., Liu, Guang, Jacobson, Sarah, Carvalho, Andrew, Rennie, Glen R., Jung, Joon, Renhowe, Paul A., Lonie, Elisabeth, Winrow, Christopher J., Hadcock, John R., Jones, Juli E., Currie, Mark G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181742/
https://ncbi.nlm.nih.gov/pubmed/34108877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.656561
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