Development of a High Throughput In Vitro Fecal Fermentation Method to Screen for TMA Production Inhibitors

OBJECTIVES: Choline is metabolized by gut bacteria to trimethylamine (TMA), which is further metabolized by the host into trimethylamine N-oxide (TMAO). There is significant interest in reducing TMAO formation to reduce atherosclerosis risk. Our objective was to develop an in vitro fermentation meth...

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Bibliographic Details
Published in:Curr Dev Nutr
Main Authors: Iglesias-Carres, Lisard, Essenmacher, Lauren, Racine, Kathryn, Neilson, Andrew
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
Subjects:
Nutritional Microbiology/Microbiome
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181532/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzab054_015
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