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High-Throughput Screening for Bacterial Glycosyltransferase Inhibitors

The enteropathogenic and enterohemorrhagic Escherichia coli NleB proteins as well as the Salmonella enterica SseK proteins are type III secretion system effectors that function as glycosyltransferase enzymes to post-translationally modify host substrates on arginine residues. This modification is un...

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Détails bibliographiques
Publié dans:Front Cell Infect Microbiol
Auteurs principaux: El Qaidi, Samir, Zhu, Congrui, McDonald, Peter, Roy, Anuradha, Maity, Pradip Kumar, Rane, Digamber, Perera, Chamani, Hardwidge, Philip R.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305410/
https://ncbi.nlm.nih.gov/pubmed/30619781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00435
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