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A Physiologically Based Pharmacokinetic (PBPK) Model of Vitamin B-6 Metabolism in the Mouse Incorporated With Visualization of Complex Compartmental Models

OBJECTIVES: To develop a compartmental model which describes vitamin B-6 metabolism in the blood and tissues of the mouse under a variety of circumstances and to develop a computer application which can utilize the data to display the movement of tracer through the various compartments. METHODS: A c...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Coburn, Stephen, Stauffer, Joel, Grobien, Kimberley, Kim, Beomjin, Townsend, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8180980/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzab059_008
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