Inhibition of SDF-1/CXCR4 Axis to Alleviate Abnormal Bone Formation and Angiogenesis Could Improve the Subchondral Bone Microenvironment in Osteoarthritis

The pathogenesis of the osteoarthritis (OA) is complex. Abnormal subchondral bone metabolism is an important cause of this disease. Further understanding on the pathology of the subchondral bone in OA may provide a new therapy. This research is about to investigate the role of SDF-1 in the subchondr...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: Qin, Hanjun, Zhao, Xingqi, Hu, Yan Jun, Wang, Shengnan, Ma, Yunfei, He, Siying, Shen, Ke, Wan, Haoyang, Cui, Zhuang, Yu, Bin
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179778/
https://ncbi.nlm.nih.gov/pubmed/34136574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8852574
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